Scleroderma, also known as systemic sclerosis, is a group of rare diseases that involve the hardening and tightening of the skin and connective tissues. Some types can also harm the blood vessels, internal organs, and the digestive tract. It is an autoimmune disease in which the immune system triggers excessive collagen production.
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Understand key symptoms, causes, diagnosis options, and treatment pathways for Scleroderma (Systemic Sclerosis). This overview is intended for patient awareness and should be followed by specialist consultation.
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About 300,000 Americans have scleroderma; it affects 75,000–100,000 adults.
Verified medical information source from NIAMS.
Visit NIAMS ReferenceAnkylosing spondylitis is a type of arthritis that primarily affects the spine. It causes inflammation of the spinal joints (vertebrae) that can lead to severe, chronic pain and discomfort. In more advanced cases, this inflammation can cause new bone to form on the spine, causing the spine to fuse in a fixed, immobile position, sometimes creating a hunched-forward posture.
AutoimmuneAntiphospholipid syndrome (APS) is an autoimmune disorder in which the immune system produces abnormal antibodies against phospholipids — a type of fat — in the blood. APS can cause blood clots to form in arteries and veins, as well as pregnancy complications such as miscarriages and preterm births. It may occur alone or with another autoimmune disease such as lupus.
AutoimmuneBehçet's disease is a rare disorder that causes blood vessel inflammation throughout the body. This can lead to numerous signs and symptoms that can seem unrelated at first. The disease can cause mouth sores, eye inflammation, skin rashes, and lesions, and genital sores. It is also known as Behçet's syndrome or Silk Road disease.