Systemic lupus erythematosus (SLE) is the most common and severe form of lupus. It is a chronic autoimmune disease in which the immune system produces antibodies that attack the body's own healthy tissue, causing widespread inflammation and damage in multiple organ systems including joints, skin, kidneys, heart, lungs, blood vessels, and brain.
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Understand key symptoms, causes, diagnosis options, and treatment pathways for Systemic Lupus Erythematosus (SLE). This overview is intended for patient awareness and should be followed by specialist consultation.
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Affects approximately 1.5 million Americans; 5 million worldwide.
Verified medical information source from NIAMS.
Visit NIAMS ReferenceAnkylosing spondylitis is a type of arthritis that primarily affects the spine. It causes inflammation of the spinal joints (vertebrae) that can lead to severe, chronic pain and discomfort. In more advanced cases, this inflammation can cause new bone to form on the spine, causing the spine to fuse in a fixed, immobile position, sometimes creating a hunched-forward posture.
AutoimmuneAntiphospholipid syndrome (APS) is an autoimmune disorder in which the immune system produces abnormal antibodies against phospholipids — a type of fat — in the blood. APS can cause blood clots to form in arteries and veins, as well as pregnancy complications such as miscarriages and preterm births. It may occur alone or with another autoimmune disease such as lupus.
AutoimmuneBehçet's disease is a rare disorder that causes blood vessel inflammation throughout the body. This can lead to numerous signs and symptoms that can seem unrelated at first. The disease can cause mouth sores, eye inflammation, skin rashes, and lesions, and genital sores. It is also known as Behçet's syndrome or Silk Road disease.