Bone Disease

Osteomalacia (Rickets in Adults)

Osteomalacia is a condition in which the bones become soft and weak due to a defect in the bone-building process. In children, this condition is called rickets. It most commonly results from vitamin D deficiency, which impairs the absorption of calcium and phosphate needed for bone mineralization. Unlike osteoporosis (loss of already mineralized bone), osteomalacia is a failure to mineralize new bone.

6

Symptoms

6

Causes

4

Treatments

3

Prevention

Condition Overview

Understand key symptoms, causes, diagnosis options, and treatment pathways for Osteomalacia (Rickets in Adults). This overview is intended for patient awareness and should be followed by specialist consultation.

Bone DiseasePrevalence Available

Need Help?

Our specialists can guide you through symptoms and treatment options.

Book Appointment

24/7 Emergency: +91 1800-MEDICARE

Symptoms

  • Bone pain and tenderness (dull, aching)
  • Muscle weakness, especially in the hip girdle
  • Difficulty walking (waddling gait)
  • Increased susceptibility to fractures
  • Muscle cramps (if hypocalcemia present)
  • Bone deformity in severe cases

Causes

  • Vitamin D deficiency (most common)
  • Malabsorption disorders (celiac disease, Crohn's)
  • Kidney or liver disease affecting vitamin D metabolism
  • Certain medications (antiepileptics)
  • Phosphate deficiency
  • Tumor-induced osteomalacia

Diagnosis

  • Blood tests (low vitamin D, calcium, phosphate; elevated PTH, alkaline phosphatase)
  • X-rays (Looser zones/pseudofractures)
  • Bone scan
  • Bone biopsy (definitive)

Treatment

  • Vitamin D supplementation (high dose)
  • Calcium supplementation
  • Treating underlying cause
  • Phosphate supplementation if deficient

Risk Factors

  • Vitamin D deficiency (limited sun exposure, dark skin, elderly)
  • Malnutrition
  • Malabsorption conditions
  • Kidney or liver disease
  • Certain medications

Prevention

  • Adequate vitamin D and calcium intake
  • Sunlight exposure
  • Treating underlying conditions promptly

Prevalence

Exact prevalence unknown; vitamin D deficiency (the main cause) affects approximately 1 billion people worldwide.