Paget's disease of bone is a chronic disease that causes bones to grow larger and weaker than normal. In Paget's disease, the process of old bone being replaced by new bone is disrupted. The new bone that forms is softer and weaker. Paget's disease most commonly occurs in the pelvis, skull, spine, and legs.
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Understand key symptoms, causes, diagnosis options, and treatment pathways for Paget's Disease of Bone. This overview is intended for patient awareness and should be followed by specialist consultation.
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Affects about 1% of people over age 40 in the United States, less common in other parts of the world.
Verified medical information source from NIAMS.
Visit NIAMS ReferenceAvascular necrosis, also called osteonecrosis, is bone death caused by reduced blood flow to the bone. When blood doesn't reach bone tissue, the bone begins to die and may eventually collapse. The hip is the most commonly affected joint, but avascular necrosis can also occur in the knee, shoulder, ankle, and wrist.
Bone DiseaseOsteopenia refers to bone mineral density that is lower than normal but not low enough to be classified as osteoporosis. People with osteopenia have weaker bones than normal and are at higher risk of developing osteoporosis and fractures. Osteopenia is a warning sign that action should be taken to improve bone health.
Bone DiseaseOsteomalacia is a condition in which the bones become soft and weak due to a defect in the bone-building process. In children, this condition is called rickets. It most commonly results from vitamin D deficiency, which impairs the absorption of calcium and phosphate needed for bone mineralization. Unlike osteoporosis (loss of already mineralized bone), osteomalacia is a failure to mineralize new bone.